The Advancement of Scaffolds Through 3D Printing Techniques for Tissue Engineering Applications

Authors:
Harvinder Singh, Priyanka Kaushal, C. Satheesh, S. Manikandan, Dinka Lale

Addresses:
Department of Mechanical Engineering, Chandigarh Group of Colleges, Mohali, Punjab, India. Department of Robotics and Automation, Dhaanish Ahmed College of Engineering, Chennai, Tamil Nadu, India. Faculty of Electrical Engineering and Applied Computing, University of Dubrovnik, Dubrovnik, Croatia.

Abstract:

An Increase in global populations at higher rates has emphasised the necessity for more advanced regenerative medicine approaches. Based on the application of tissue-engineered scaffolds with an adhesion, proliferation, and branching template for cells, a novel type of bio-functional scaffolds is being developed to restore degenerating tissue with function and enhance patients' quality of life. This paper primarily focuses on the most essential applications of ceramic materials. Ceramics are appreciated due to their inherent hardness, body inertness, and toughness, and are thus very suitable for use as biomaterials for bone filler substitutes. Their inbuilt brittleness has, however, restricted them until now. Technological innovations in 3D printing have enabled the production of bioceramics that create scaffolds with a complex architecture and enhanced mechanical strength. The current paper synthesises information from a purposive sample of peer-reviewed scientific publications to explore such advancements. A comparative model that describes varying 3D printing technologies serves as the central analytical framework. This overview considers the size, fabrication methods, material components, and functional advantages of 3D ceramic scaffolds. For instance, a hydroxyapatite (HAp) bioglass alumina composite scaffold, achieved through these methods, possesses appropriate compressive and tensile strength with an optimum range of porosity in 20–25%. 

Keywords: Tissue Engineering; 3D Printing; Ceramic Scaffolds; Bioceramics and Hydroxyapatite; Fabrication Methods; Central Analytical Framework; Regenerative Model; Additive Manufacturing.

Received: 10/09/2024, Revised: 05/11/2024, Accepted: 13/12/2024, Published: 07/06/2025

DOI: 10.64091/ATIEL.2025.000122

AVE Trends in Intelligent Energy Letters, 2025 Vol. 1 No. 1 , Pages: 11-20

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